Map of the B95-8 EBV genome. Vertical lines indicate BamHI restriction sites. By convention, the restriction fragments are designated alpbabetically, with the A fragment being the largest, the B fragment the next largest, and so on. Open reading frames are identified by making reference to the appropriate BamHI restriction fragment. Thus, BKRF1 indicates the BamHI-K fragment, rightward open reading frame, 1 (EBNA-1). (Source: Ref. 12)