Table 2.

Clinical and pathological characteristics of patients undergoing liver resection for large hepatocellular carcinoma

	Liver resection		P-value
	Fulfilling UCSF criteria	Exceeding UCSF criteria
Patients, n	32	27
Mean age, years (range)	63 (49–73)	65 (52–72)	0.1
Aetiology
Hepatitis B	16 (50%)	13 (48%)	0.3
Hepatitis C	10 (31%)	5 (19%)
Other	6 (19%)	9 (33%)
CTP score, mean (range)	5 (5–6)	6 (5–6)	0.2
MELD score, mean (range)	8 (7–14)	9 (8–14)	0.1
Tumour size, cm, mean (range)	6 (2–6.5)	9 (6.5–12)	0.008
Solitary	28	19	0.07
Nodules, n, mean	2	3	0.04
Microvascular invasion, n	20 (62%)	21 (78%)	0.03
Satellitosis, n	10 (31%)	8 (30%)	0.1
Lobectomy, n	23	9	<0.01
Extended hepatectomy (trisectorectomy), n	9	18	0.02
Tumour-free resection margin ≥1 cm	29	18	0.03
Differentiation
Good, n	19	12
Moderate, n	13	10	0.08
Poor, n	7	5
ALTSG staging
III, n	36	22
IV A1, n	3	3	0.04
IV A2, n	0	2
Median follow-up	33 months	27 months

UCSF, University of California San Francisco; CTP, Child-Turcotte-Pugh; MELD, model for end-stage liver disease; ALTSG, American Liver Tumor Study Group