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. Author manuscript; available in PMC: 2009 Dec 2.
Published in final edited form as: Transplantation. 2008 Aug 27;86(4):615–619. doi: 10.1097/TP.0b013e3181821bac

FIGURE 1.

FIGURE 1

Absolute neutrophil counts (ANC) in CP group (A) and TBI group (B). In CP-treated recipients, neutropenia was observed in dose-dependent fashion and the nadir of ANC was around 500/mm3 on post-transplantation day 2. ANC then recovered to normal (>3000/mm3) by day 5 in groups A (CP 40 mg/kg×3) and B (50 mg/kg×3), and by day 8 in group C(CP 50 mg/kg×4). In TBI treated recipients, neutropenia was not observed with 1.5×1 Gy of TBI. With TBI 2.3 Gy, the recipients showed earlier recovery of ANC by day 15. Similar levels of neutropenia were observed in the recipients treated with TBI 1.25×2 and 1.5×2 Gy between days 8 and 18. After day 18, ANC was higher in group I, because of higher levels of donor chimeric neutrophils. Lymphocyte subsets in group C (C) and in group I (D). There was no significant difference in absolute counts of CD3, CD4, CD8 and NK cells between groups C and I. B cell absolute counts were significantly higher in group C (CP 50×4 mg/kg) on days 0, 5 and 12 than those in group I (TBI 1.5 Gy×2).