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. Author manuscript; available in PMC: 2009 Dec 2.
Published in final edited form as: Hum Genet. 2008 Jul 25;124(2):147–154. doi: 10.1007/s00439-008-0532-6

Figure 4. Impact of adjusting for admixture on genotypic association results for 208 SNPs from eight T2DM candidate genes.

Figure 4

Relationship between absolute δ and the impact of admixture (using FRAPPE generated individuals ancestral estimates) on genotypic tests of association for dominant, additive, and recessive models in 208 SNPs from eight candidate gene studies for T2DM. Absolute δ, defined as the absolute difference between the Yoruban African major allele frequency and corresponding allele frequency in European Americans, is plotted along the x-axis while the admixture impact, defined as the difference between the −log(unadjusted) and −log(admixture adjusted) P-value is plotted along the y-axis.