Table 4.
Linear regression analysis combining all subjects to evaluate change in creatinine and change in risk factor
| Risk factors (per SD) | Unadjusted, OR (95% CI) | p | Adjusted1, OR (95% CI) | p |
|---|---|---|---|---|
| CRP, mg/l (15.4) | −0.011 (−0.055 to 0.032) | 0.61 | −0.012 (−0.055 to 0.031) | 0.57 |
| IL-6, pg/ml (2.9) | 0.052 (0.022 to 0.082) | 0.001 | 0.041 (0.011 to 0.071) | 0.0071 |
| Fibrinogen, mg/dl (72.7) | 0.027 (−0.003 to 0.057) | 0.07 | 0.017 (−0.012 to 0.047) | 0.24 |
| Factor VII, % (24.3) | −0.029 (−0.071 to 0.014) | 0.19 | −0.022 (−0.064 to 0.020) | 0.31 |
| Factor VIII, % (50.3) | 0.054 (0.024 to 0.083) | <0.001 | 0.048 (0.018 to 0.077) | 0.002 |
| HDL, mg/dl (7.6) | 0.010 (−0.034 to 0.053) | 0.66 | 0.005 (−0.038 to 0.049) | 0.82 |
| LDL, mg/dl (26.6) | −0.035 (−0.079 to 0.010) | 0.13 | −0.026 (−0.071 to 0.019) | 0.25 |
| Triglycerides, mg/dl (79.7) | 0.025 (−0.018 to 0.068) | 0.26 | 0.029 (−0.013 to 0.072) | 0.17 |
1
Adjusted for age, gender, race, SBP, diuretics, prevalent CVD, internal carotid IMT.