Table 4.
Hemodynamic measurements for five pigs having isovolumetric hemodilution
| Total hemoglobin concentration | ||||
|---|---|---|---|---|
| Characteristic | 13 g/dl | 10 g/dl | 7 g/dl | 4 g/dl |
| Number of measurements | 3 | 5 | 5 | 5 |
| Arterial total hemoglobin (g/dl)a | 13.6 (13 to 14.6) | 9.7 (9.3 to 10.5) | 6.9 (6.5 to 7.4) | 3.9 (3 to 4.7) |
| Cardiac output (ml/min/kg) | 110 ± 47 | 131 ± 37 | 160 ± 77 | 168 ± 98 |
| Femoral artery flow (ml/min/kg) | 4.8 ± 1.6 | 6.0 ± 2.2 | 5.9 ± 1.9 | 6.1 ± 2.0 |
| Heart rate (beats/minute) | 97 ± 9*4 | 113 ± 16 | 127 ± 29 | 155 ± 39*13 |
| Systolic blood pressure (mmHg) | 97 ± 2 | 99 ± 10 | 99 ± 10 | 91 ± 22 |
| Diastolic blood pressure (mmHg) | 69 ± 4 | 65 ± 9 | 69 ± 13 | 54 ± 16 |
| Mixed SmvO2 (%) | 83.0 ± 4.4*4 | 73.8 ± 5.5 | 69.0 ± 11.4 | 61.2 ± 19.3*13 |
| Hind limb StO2 (%) | 89.0 ± 2.8*10 and 7 | 80.0 ± 6.3*13 | 82.7 ± 5.6*13 | 84.1 ± 6.2 |
| Hind limb THI (arbitrary) | 8.3 ± 1.1*4 | 7.8 ± 1.2 | 7.3 ± 1.0 | 6.8 ± 1.0*13 |
Data presented as mean ± standard deviation. a Mean and range shown since the variable was controlled to have no overlap in values. A nonparametric Dunn's multiple comparison test was used to study differences in mean values. *P < 0.05 for the hemoglobin column(s) indicated.
The tissue hemoglobin index was statistically different only when total hemoglobin concentration changed from 13 to 4 g/dl. SmvO2, mixed venous hemoglobin oxygen saturation; StO2, tissue hemoglobin oxygen saturation.