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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: JALA Charlottesv Va. 2009 Dec 1;14(6):383–399. doi: 10.1016/j.jala.2009.07.003

Figure 7.

Figure 7

Ratiometric analysis of changes in glycerophosphocholine (GPCho) lipid ion abundances determined between age matched control and diabetic rat erythrocytes, 36 weeks after treatment with streptozotocin, in the presence or absence of an internal standard. Data were obtained by positive ion mode ESI-MS/MS analysis, via precursor ion scanning for the characteristic phosphocholine ion at m/z 184 to identify [M+H]+ precursor ions. Data values are displayed as mean ± standard deviation. (S.D.) from n=5 control and n=4 diabetic rats. (A) Comparison of age matched control and diabetic rat erythrocytes (with internal standard). (B) Comparison of age matched control and diabetic rat erythrocytes (without internal standard). (C) Visualization of the fold change (expressed as the ratio of diabetic/control lipid area intensity) in the abundances of individual GPCho lipid ions observed between age matched control and diabetic rat erythrocytes from panel A. (D) Visualization of the fold change (expressed as the ratio of diabetic/control lipid area intensity) in the abundances of individual GPCho lipid ions observed between age matched control and diabetic rat erythrocytes from panel B. The solid line indicates the mean of the measurements, while the dashed lines indicate ±1.645 S.D. (i.e., 90% confidence intervals).