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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Osteoarthritis Cartilage. 2009 Mar 24;17(9):1244–1251. doi: 10.1016/j.joca.2009.03.007

Table 1.

Modified Mankin Score used for histological analysis.

I Structure Grade
Normal 0
Superficial layer disrupted 1
Superficial layer absent 2
Irregular Surface 3
Fissures into the middle zone 4
Slight disorganization 5
Fissures into the deep zone 6
Chaotic disorganization 7

II Cellular abnormalities

Normal 0
Hypocellularity 1
Large Clones 2

III Matrix Staining

 Normal 0
Staining reduced in middle layer 1
Staining reduced in territorial matrix of middle or deep layer 2
Staining present in the interterrritorial matrix and reduced in
the territorial matrix
3
Staining reduced in both territorial and interterritorial matrices 4

Maximum Score   13