Table 2.

Interaction of Group with Change in Absolute rCMRglc

Cluster-level						Peak Voxel
Increase in MA group and / or Decrease in Control group
		Volume corrected Spatial Extent p Value	Max. Cluster Size (voxels)	p<.01 voxels in Total ROI	% ROI	Volume corrected Voxel Height p Value	Z- Score	Coordinates (x, y, z)
Parietal Lobe	Left	<.0005*	3328	3336	73%	.019	4.37	−30	−54	64
	Right	<.0005*	1894	1922	47%	.030	4.20	20	−82	34
Lateral Orbitofrontal	Left	.107	92	199	16%	.035	3.83	−42	50	−6
	Right	.071	114	213	19%	.007	4.32	44	22	−14
Insula	Left	.322	19	45	4%	.362	2.69	−42	18	−2
	Right	.276	24	29	2%	.028	3.78	48	18	−6
ACCsg	Left	.018	179	219	22%	.079	3.29	−2	46	16
	Right	.035	136	175	23%	.048	3.49	8	28	24
Thalamus	Left
	Right	.068	85	85	15%	.040	3.59	12	−28	0

Within Group simple effects: Increase in MA group
Parietal Lobe	Left	<.0005*	4539	4540	99%	<.0005*	5.30	−28	−78	46
	Right	<.0005*	4023	4023	98%	<.0005*	5.42	20	−82	34
Lateral Orbitofrontal	Left	<.0005*	984	984	81%	.009	4.25	−42	50	−6
	Right	<.0005*	872	872	78%	<.0005*	5.04	44	22	−14
Medial Orbitofrontal	Left	.019	195	255	27%	.009	4.15	−26	48	−14
	Right	.034	149	222	26%	.119	3.24	22	44	−16
Insula	Left	<.0005*	746	752	64%	.034	3.73	−34	22	0
	Right	<.0005*	609	681	55%	.001*	4.87	48	18	−6
ACCsg	Left	<.0005*	889	889	91%	.008	5.84	−6	36	16
	Right	<.0005*	723	723	96%	.006	4.18	6	26	24
ACCig	Left	.075	29	38	20%	.064	2.90	−8	38	−14
	Right	.039	55	55	40%	.015	3.41	4	42	−8

Included in tables 2 and 3 are those of the 20 ROIs that were assessed (10 in each hemisphere) where the noted effect attained volume-corrected probability <.05 at the peak voxel, and for comparative purposes, the homologous ROI in the opposite hemisphere. The size and spatial-extent probability associated with the largest cluster, the total proportion of the ROI constituted by all clusters, and the peak voxel Z-score, associated probability, and MNI coordinates are tabled. ACCsg = supragenual anterior cingulate cortex, ACCig = infragenual anterior cingulate cortex

^*Statistical significance maintained after applying the Bonferroni correction for 40 comparisons (.05 / 40 = .0012).