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. Author manuscript; available in PMC: 2009 Dec 2.
Published in final edited form as: Cancer Res. 2008 Apr 1;68(7):2498–2506. doi: 10.1158/0008-5472.CAN-07-5165

Figure 1. Gene structure and location of SNPs in the SHMT1 gene.

Figure 1

tagSNPs that comprise the haplotype assayed among 1,770 Caucasian subjects (Mayo Clinic, MN and Duke University, NC, 1999–2006) are shown below the gene. SNPs previously reported to be associated with cancer (39, 40) in the same region are shown above the gene. Adapted from (39).

Shaded regions in the linkage disequilibrium (LD) plot indicate the strength of LD between pair-wise combinations of SNPs (white: r2 = low LD, black: r2 = high LD).