TABLE 2.
SCCmec elements identified in MRSAa
| SCCmec typeb | Reported namec | Major characteristics of J regionsd | Representative strain(s) | Reference(s) and/or accession no.e |
|---|---|---|---|---|
| I (1B) | I | J1, subtype 1-specific ORFs (pls); J3, dcs | NCTC10442, COL | 9, 18 |
| I.2 | J1, subtype 2-specific ORFs; J3, dcs and pUB110 | PL72 | 18 | |
| II (2A) | II | J1, subtype 1-specific ORFs (kdp); J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110 | N315 | 18 |
| IIb | J1, subtype 2-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcs | JCSC3063 | 7 | |
| IIB | J1, subtype 3-specific ORFs; J2, subtype 1-specific ORFs; J3, dcs and pUB110 | AR05/0.1345 | 20 | |
| IIE | J1, subtype 3-specific ORFs; J2, short J2 region the same as subtype 1 and Tn554; J3, dcs and pUB110 | AR13.1/3330.2 | 20 | |
| II.4.1.1 | J1, subtype 4-specific ORFs; J2, subtype 1-specific ORFs and Tn554; J3, dcs and pUB110 | RN7170 | 13 | |
| III (3A) | III | J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs and pT181 | 85/2082, ANS46 | 9, 18 |
| IIIA | J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs and ΨTn554; J3, subtype 1-specific ORFs, pT181, and SCCHg carrying ccrC | HU25 | 18 | |
| IV (2B) | IVa | J1, subtype 1-specific ORFs; J3, dcs | CA05, MW2 | 15 |
| IVb | J1, subtype 2-specific ORFs; J3, dcs | 8/6-3P | 15 | |
| IVc | J1, subtype 3-specific ORFs; J3, dcs and Tn4001 | 81/108 | 16 | |
| IVc | J1, subtype 3-specific ORFs; J3, dcs | 2314 | AY271717 | |
| IVA | J1, subtype 3-specific ORFs; J3, dcs and pUB110 | cm11 | EU437549 | |
| IVE | J1, subtype 3-specific ORFs; J3, subtype 2-specific ORFs | AR43/3330.1 | 20 | |
| IVd | J1, subtype 4-specific ORFs; J3, dcs | JCSC4469 | 16 | |
| IVg | J1, subtype 5-specific ORFs; J3, dcs | M03-68 | 14 | |
| IVh | J1, subtype 6-specific ORFs; J3, dcs | EMRSA-15 | 17 | |
| IVi | J1, subtype 7-specific ORFs; J3, dcs | JCSC6668 | 2 | |
| IVj | J1, subtype 8-specific ORFs; J3, dcs | JCSC6670 | 2 | |
| IV (2B&5) | IV variant | J1, subtype 3-specific ORFs; J3, SCC carrying ccrC | ZH47 | 6 |
| V (5C2) | V | J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFs | WIS(WBG8318) | 10 |
| V (5C2&5) | VT, VII | J1, subtype 2-specific ORFs; J2, sutype 2-specific ORFs; J3, SCC carrying ccrC | TSGH17, PM1 | 3, 22 |
| VI (4B) | VI | J1, subtype 1-specific ORFs; J3, dcs | HDE288 | 19 |
| VII (5C1) | 5C1 | J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFs | JCSC6082 | 1 |
| VIII (4A) | VIII | J1, subtype 1-specific ORFs; J2, subtype 1-specific ORFs; J3, subtype 1-specific ORFs | C10682, BK20781 | 23; FJ670542 |
SCCmec elements that satisfy the following criteria are listed as follows: entire regions of SCCmec elements have been sequenced, or the essential parts of the mec gene complex and the ccr gene complex have been fully sequenced.
The first categories for classifying SCCmec elements. The combinations of the ccr gene complex and the mec gene complex carried by the elements are indicated in parentheses.
The names reported in original literature are listed. Assigned numbers or names that specify these elements would be given by IWG-SCC and would be seen at the website (http://www.SCCmec.org [under construction]).
Key loci are indicated in parentheses. pls, plasmin-sensitive surface protein; dcs, downstream constant segment; kdp, potassium-dependent ATPase operon.
GenBank/EMBL/DDBJ accession numbers are indicated in cases of direct submission.