TABLE 1.
Susceptibilities of Desulfovibrio isolates from humans to 20 antimicrobial agents
| Species and antimicrobial agent (no. of isolates) | MIC (μg/ml)a |
||
|---|---|---|---|
| Range | 50% | 90% | |
| Desulfovibrio spp. (n = 23) | |||
| Antianaerobic | |||
| Sulbactam-ampicillin | 0.064-6 | 0.38 | 6 |
| Piperacillin | 32->256 | >256 | >256 |
| Piperacillin-tazobactam | 16->256 | >256 | >256 |
| Cefoxitin | 16->256 | >256 | >256 |
| Cefotaxime | 0.047->256 | 1.5 | >256 |
| Meropenem | 0.023-12 | 0.19 | 4 |
| Clindamycin | 0.016-0.25 | 0.125 | 0.19 |
| Chlorampenicol | 1.5-12 | 4 | 8 |
| Metronidazole | <0.016-1.5 | 0.125 | 0.25 |
| Others | |||
| Ampicillin | 0.19-24 | 0.75 | 8 |
| Cefoperazone | 12->256 | >256 | >256 |
| Sulbactam-cefoperazone | 1->256 | 4 | >256 |
| Cefalothin | 16->256 | >256 | >256 |
| Ceftazidime | 2->256 | 6 | >256 |
| Cefpirome | 0.5->256 | 4 | >256 |
| Erythromycin | 0.064-4 | 0.5 | 1.5 |
| Minocycline | 0.19-24 | 6 | 24 |
| Ciprofloxacin | 0.125->32 | 0.5 | >32 |
| Levofloxacin | 0.094->32 | 0.75 | >32 |
| Sulfamethoxazole-trimethoprim | >32 | >32 | >32 |
| D. fairfieldensis (n = 8)b | |||
| Antianaerobic | |||
| Sulbactam-ampicillin | 4-6 | ||
| Piperacillin | >256 | ||
| Piperacillin-tazobactam | >256 | ||
| Cefoxitin | 64->256 | ||
| Cefotaxime | 0.047->256 | ||
| Meropenem | 2-12 | ||
| Clindamycin | 0.032-0.19 | ||
| Chloramphenicol | 3-6 | ||
| Metronidazole | <0.016-0.38 | ||
| Others | |||
| Ampicillin | 4-8 | ||
| Cefoperazone | >256 | ||
| Sulbactam-cefoperazone | 24->256 | ||
| Cefalothin | >256 | ||
| Ceftazidime | >256 | ||
| Cefpirome | >256 | ||
| Erythromycin | 0.5-4 | ||
| Minocycline | 4-24 | ||
| Ciprofloxacin | >32 | ||
| Levofloxacin | >32 | ||
| Sulfamethoxazole-trimethoprim | >32 | ||
| D. desulfuricans Essex 6 (n = 7)c | |||
| Antianaerobic | |||
| Sulbactam-ampicillin | 0.125-1.5 | ||
| Piperacillin | >256 | ||
| Piperacillin-tazobactam | 16->256 | ||
| Cefoxitin | >256 | ||
| Cefotaxime | 0.047-6 | ||
| Meropenem | 0.064-0.25 | ||
| Clindamycin | 0.094-0.25 | ||
| Chloramphenicol | 1.5-12 | ||
| Metronidazole | 0.064-1.5 | ||
| Others | |||
| Ampicillin | 0.19-2 | ||
| Cefoperazone | 16->256 | ||
| Sulbactam-cefoperazone | 3->256 | ||
| Cefalothin | 3->256 | ||
| Ceftazidime | 3->256 | ||
| Cefpirome | 0.5-32 | ||
| Erythromycin | 0.38-0.75 | ||
| Minocycline | 2-12 | ||
| Ciprofloxacin | 0.19-2 | ||
| Levofloxacin | 0.25-3 | ||
| Sulfamethoxazole-trimethoprim | >32 | ||
| D. desulfuricans MB (n = 6)d | |||
| Antianaerobic | |||
| Sulbactam-ampicillin | 0.064-0.25 | ||
| Piperacillin | 32->256 | ||
| Piperacillin-tazobactam | 32-96 | ||
| Cefoxitin | 16->256 | ||
| Cefotaxime | 0.5-1.5 | ||
| Meropenem | 0.023-0.064 | ||
| Clindamycin | 0.094-0.19 | ||
| Chloramphenicol | 1.5-4 | ||
| Metronidazole | 0.016-0.38 | ||
| Others | |||
| Ampicillin | 0.19-0.38 | ||
| Cefoperazone | 12-24 | ||
| Sulbactam-cefoperazone | 1-3 | ||
| Cefalothin | 2-6 | ||
| Ceftazidime | 2-4 | ||
| Cefpirome | 0.5-2 | ||
| Erythromycin | 0.38-1 | ||
| Minocycline | 3-8 | ||
| Ciprofloxacin | 0.125-0.38 | ||
| Levofloxacin | 0.25-0.5 | ||
| Sulfamethoxazole-trimethoprim | >32 | ||
| D. piger (n = 2)e | |||
| Antianaerobic | |||
| Sulbactam-ampicillin | 0.5-1 | ||
| Piperacillin | >256 | ||
| Piperacillin-tazobactam | >256 | ||
| Cefoxitin | 16 | ||
| Cefotaxime | 1-1 | ||
| Meropenem | 0.032-0.19 | ||
| Clindamycin | 0.016-0.016 | ||
| Chloramphenicol | 1.5-3 | ||
| Metronidazole | 0.032-0.5 | ||
| Others | |||
| Ampicillin | 12-32 | ||
| Cefoperazone | 12-32 | ||
| Sulbactam-cefoperazone | 1-1.5 | ||
| Cefalothin | 96->256 | ||
| Ceftazidime | 3-3 | ||
| Cefpirome | 0.75-4 | ||
| Erythromycin | 0.016-0.125 | ||
| Minocycline | 0.19-1 | ||
| Ciprofloxacin | 0.125-0.19 | ||
| Levofloxacin | 0.095-0.125 | ||
| Sulfamethoxazole-trimethoprim | >32 | ||
a
50% and 90%, MIC50 and MIC90, respectively.
b
One isolate from pouchitis, five from stool specimens, and two from tongue coating.
c
One isolate from appendicitis, two from stool specimens, and four from tongue coating.
d
One isolate from blood, three from pouchitis, and two from appendicitis.
e
Both isolates from pouchitis.