TABLE 2.

Microsatellite haplotypes among different pfdhfr genotypes in P. falciparum parasite population

pfdhfr mutation or group (no. of isolates)a	Haplotype	Microsatellite haplotype at kbb:							Pic
		−7.7	−5.2	−3.9	−0.3	0.3	+1.28	+5.6
A16N51C59N108I164 (9)	H1	10	14	13	17	16	10	11	0.11
	H2	11	13	13	17	16	10	11	0.11
	H3	10	21	17	17	12	12	11	0.11
	H4	10	21	21	17	14	11	7	0.11
	H5	10	21	17	18	13	11	11	0.11
	H6	10	21	13	17	12	11	11	0.11
	H7	10	14	13	17	16	10	7	0.11
	H8	10	21	17	17	12	11	7	0.11
	H9	10	14	13	17	13	11	7	0.11
A16N51R59N108I164 (92)	H1	10	14	13	17	16	10	11	0.55
	H10	10	13	13	17	16	10	11	0.11
	H7	10	14	13	17	16	10	7	0.044
	H11	10	11	13	17	16	10	11	0.033
	H12	10	14	13	17	16	11	11	0.033
	H13	10	14	13	17	17	10	11	0.033
	H14	10	14	13	17	16	10	12	0.022
	H15	10	14	13	17	15	10	11	0.022
	H16	10	11	13	13	12	11	16	0.011
	H17	10	11	18	17	12	11	12	0.011
	H18	10	14	13	17	16	10	16	0.011
	H19	10	11	18	17	16	10	11	0.011
	H20	10	11	23	17	16	10	11	0.011
	H21	10	16	17	17	12	11	7	0.011
	H22	10	13	13	17	15	10	11	0.011
	H23	10	13	13	17	16	10	10	0.011
	H24	10	12	13	17	16	10	11	0.011
	H25	11	14	13	17	16	10	11	0.011
	H26	10	21	13	17	12	10	7	0.011
	H27	19	14	13	17	16	10	11	0.011
	H28	11	14	13	17	17	10	11	0.011
A16I51R59N108I164 (14)	H1	10	14	13	17	16	10	11	0.50
	H13	10	14	13	17	17	10	11	0.21
	H29	10	14	13	17	18	10	11	0.071
	H9	10	14	13	17	13	11	7	0.071
	H12	10	14	13	17	16	11	11	0.071
	H30	10	14	13	18	16	10	11	0.071
A16N51R59N108L164 (3)	H1	10	14	13	17	16	10	11	1.00
A16I51R59N108L164 (52)	H1	10	14	13	17	16	10	11	0.85
	H10	10	13	13	17	16	10	11	0.134
	H31	10	14	13	15	16	10	11	0.019
Thai isolates	H1	10	14	13	17	16	10	11

^aMutated amino acids are shown in bold.

^bLocations of microsatellites around pfdhfr in kb. Negative positions are upstream of pfdhfr and positive positions are downstream of pfdhfr (20).

^cP_i is the frequency of the ith haplotype in the population.