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. 2009 Sep 28;53(12):5022–5025. doi: 10.1128/AAC.01026-09

FIG. 1.

FIG. 1.

Cumulative mortality of mice infected with Rhizopus microsporus FMR 3542 (A), IHEM 4770 (B), UTHSC 01-983 (C), or UTHSC R-3466 (D) and treated with LAMB or POS. a, P < 0.05 for comparison with the control; b, P < 0.05 for comparison with POS 40; c, P < 0.05 for comparison with POS 20 BID. LAMB 10, liposomal amphotericin B administered at 10 mg/kg i.v. once a day; POS 40, posaconazole administered at 40 mg/kg p.o. once a day; POS 20 BID, posaconazole administered at 20 mg/kg p.o. twice a day. Groups of 10 mice were randomly established, one for each treatment and one as a control.