TABLE 1.
Correlation between production of CPB, CPA, and PFO in vitro and lethality in the i.g. and i.d. mouse models using whole cultures of C. perfringens type C
| Straina | Toxin type | Lethality (%) |
In vitro toxin productionb |
|||
|---|---|---|---|---|---|---|
| i.d. | i.g. | CPB (μg/ml) | CPA (U/ml, 103) | PFO (log2 titer) | ||
| CN1797 | C | 92 | 75 | 18.9 | 5.5 | 3.9 |
| CN2109 | C | 100 | 83 | 12.8 | 9.2 | 3.1 |
| CN3685 | C | 100 | 93 | 13 | 6 | 2.9 |
| CN3686 | C | 92 | 0 | 6 | 1.2 | 1.9 |
| CN3717 | C | 83 | 67 | 1 | 0.5 | 2 |
| CN3758 | C | 42 | 0 | 14.8 | 5.2 | <1 |
| CN3955 | C | 100 | 50 | 30.9 | 9.3 | 3.6 |
| CN5383 | C | 100 | 0 | 23.5 | 3.6 | 1.6 |
| CN5388 | C | 58 | 0 | 3 | 0.9 | 1.8 |
| CN685 | C | 100 | 0 | 8.9 | 1.1 | 2.2 |
| CN885 | C | 100 | 58 | 23.6 | 6.3 | 2.6 |
| CN886 | C | 100 | 92 | 24.1 | 5.1 | 4.2 |
| JGS1071 | C | 58 | 0 | 2.5 | 0.9 | 3.1 |
| NCTC 10719 | C | 75 | 0 | 2.7 | 0.7 | <1 |
| ATCC 3624 | A | 0 | 0 | 0.8 | 1.7 | |
| Sterile TGY | 0 | 0 | ||||
a
Each mouse received approximately 3 × 108 CFU.
b
Determined for a previous study (2).