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Effects of sse deletion on GAS virulence in subcutaneous and intraperitoneal infections of mice. Groups of eight female CD-1 mice were subcutaneously infected with 1.4 × 108 CFU of MGAS5005, 1.6 × 108 CFU of the Δsse strain, or 1.5 × 108 CFU of the Δsse-sse strain (A) or intraperitoneally infected with 9.1 × 107 CFU of MGAS5005 or 9.4 × 107 CFU of the Δsse strain (B). The data represent the survival rates of the infected mice.
