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. 2009 Oct 5;77(12):5300–5310. doi: 10.1128/IAI.00501-09

FIG. 3.

FIG. 3.

Histological analysis of murine lungs after MAb RB6-8C5 administration. Histological sections of lungs from C3H/HeN mice that were given PAO1 (100 CFU) only (A), MAb RB6-8C5 (0.200 mg i.p. once only) (B), or MAb RB6-8C5 followed by P. aeruginosa strain PAO1 (100 CFU i.n. 24 h after RB6-8C5 administration) (C). Mice were sacrificed 24 h after either MAb RB6-8C5 or PAO1 challenge. Magnification, ×40. Images in panels A and B show normal histologic appearance, whereas the section in panel C shows consolidation and histologic changes consistent with an acute pneumonia.