Table 2.
Tissue distribution of alternatively spliced gephyrin sequences
| Probe | Brain | Muscle | Heart | Liver | Lung | Spleen | Kidney | Testis |
|---|---|---|---|---|---|---|---|---|
| Exon 2 (C1) | (5.1) | (5.1) | (5.1) | (5.1) | (5.1) | (5.1) | (5.1) | (5.1) |
| Exon 3 (C2) | (6.5) | 6.5 | n.d. | n.d. | ||||
| 3.6 | 3.6 | 3.6 | 3.8 | 3.6 | 3.6 | |||
| Exon 9 (C3) | n.d. | (6.5) | (6.5) | n.d. | n.d. | 4.5 | ||
| 3.6 | 3.6 | 3.8 | (3.8) | 3.6 | 3.6 | |||
| Exon 11 (C4) | n.d. | n.d. | n.d. | 5.1 | n.d. | n.d. | n.d. | n.d. |
| Exon 13 (C5) | n.d. | 6.5 | (6.5) | n.d. | n.d. | n.d. | n.d. | n.d. |
| Exon 19 (C6) | 5–9 | 6.5 | 6.5 | n.d. | n.d. | ≈9 | ||
| 3.6 | 3.6 | 3.8 | 3.6 | 3.6 | ||||
| Exon 21 (C7) | 6.5 | |||||||
| 5.1 | 5.1 | 5.1 | 5.1 | 5.1 | 5.1 | 5.1 | 5.1 |
The numbers indicate the lengths of the gephyrin transcripts in kb as detected with the probes indicated. A exon 11-specific probe cross-hybridized strongly to a band of 1.6 kb in all tissues examined; the nature of this transcript is presently unclear. Parentheses indicate RNAs of low abundance. Putative degradation products (2.2–2.6 kb) of the major 3.6- to 3.8-kb gephyrin transcript are not included. n.d., no transcripts detected.