FIG. 6.

Expression of various iraD::luxCDABE reporters in response to DNA damage. (A) Gray bars show expression in response to H₂O (Ctrl), and black bars show expression in response to 1 μg of AZT/ml for at least two isolates. RLU, relative luminescence units (bioluminescence counts per minute, normalized to the OD₆₀₀). (B) iraD::luxCDABE expression for the 600-bp promoter fusion (P1 and P2), the distal promoter P1, and the proximal promoter P2 after treatment with either AZT or peroxide as indicated, normalized to untreated controls. Each data point represents the median value derived from data from at least eight isolates.