TABLE 2.
Detection of endotoxemia in association with bacteremia among studies of four specified GN infections (restricted studies)
| Organism and authors, yr (reference) | Assay sensitivity limit (ng/ml) | No. (%) of patients |
|
|---|---|---|---|
| Limulus positive | Limulus negative | ||
| Neisseria meningitidis | |||
| Bjorvatn et al., 1984 (4) | 0.005 | 4 | 0 |
| Brandtzaeg et al., 1989 (5) | 0.005 | 24 | 11 |
| Gardlund et al., 1995 (20) | 0.01 | 9 | 1 |
| Prins et al., 1998 (48) | 0.04 | 30 | 1 |
| Harthug et al., 1983 (25) | 0.5 | 2 | 2 |
| Subtotal for N. meningitidis | 69 (82) | 15 (18) | |
| Yersinia pestis | |||
| Butler et al., 1973 (7) | 0.5 | 2 | 0 |
| Butler et al., 1976 (8) | 5 | 3 | 2 |
| Subtotal for Y. pestis | 5 (71) | 2 (29) | |
| Burkholderia pseudomallei | |||
| Simpson et al., 2000 (53) | 0.002 | 38 (93) | 3 (7) |
| Salmonella serovar Typhi | |||
| McGladdery et al., 1993 (44) | 0.04 | 0 | 16 |
| Adinolfi et al., 1987 (1) | 0.3 | 7 | 7 |
| Butler et al., 1978 (6) | 1 | 0 | 13 |
| Magliulo et al., 1976 (40) | 1 | 8 | 4 |
| Subtotal for S. Typhi | 15 (27) | 40 (63) | |