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. 2009 Oct 7;47(12):4180–4182. doi: 10.1128/JCM.01192-09

TABLE 1.

Reported cases of anaerobic poststernotomy wound infection

Yr (na) Age/gender Type of surgery Prophylaxis Bacteriological findings
Antimicrobial therapy Outcome Reference
Mediastinal fluid Blood cultures
1976 (1) 65/Male Coronary bypass Cephalotin Bacteroides fragilis Bacteroides fragilis Clindamycin Cured 7
1985 (2) 65/Male Coronary bypass Cephapirin Bacteroides brevis, Staphylococcus epidermidis Bacteroides brevis Clindamycin, ticarcillin, gentamicin Cured 15
44/Male Coronary bypass Cephapirin Bacteroides fragilis, Staphylococcus epidermidis Bacteroides fragilis Clindamycin, nafcillin, gentamicin Cured
1988 (1) 48/Male Coronary bypass Cefamandole Bacteroides oralis, Staphylococcus epidermidis, α-hemolytic streptococci Bacteroides fragilis Clindamycin, vancomycin Cured 8
1989 (15b) Various Various Various 10 Peptostreptococcus isolates (including 4 Finegoldia magnac isolates/), and 4 Bacteroides, 2 Propionibacterium, and 2 Clostridium isolates Not detailed Various Not detailed 4
1996 (2) 43/Female Coronary bypass Unknown Staphylococcus aureus, Finegoldia magnac Staphylococcus aureus Vancomycin, gentamicin Cured 6
29/Male Cardiac assist device Unknown Propionibacterium acnes, Staphylococcus epidermidis Propionibacterium acnes Vancomycin, penicillin Cured
2001 (4) 7/Female Ventricular septal defect 1st-generation cephalosporin Prevotella intermedia, Peptostreptococcus micros Negative Imipenem, amoxicillin-clavulanate Cured 5
3/Female Ventricular septal defect 1st-generation cephalosporin Staphylococcus aureus, Bacteroides thetaiotaomicron, Peptostreptococcus prevotii Staphylococcus aureus Clindamycin, vancomycin Cured
5/Female Fallot's tetralogy 1st-generation cephalosporin Escherichia coli, Clostridium perfringens Escherichia coli Clindamycin, vancomycin Cured
2/Male Transposition of the great vessel Penicillin Prevotella melaninogenica, Peptostreptococcus species, Propionibacterium acnes Prevotella melaninogenica Ticarcillin-clavulanate, amoxicillin-clavulanate Curedd
2008 (1) 50/Male Coronary bypass Cefamandole Finegoldia magnac Negative Metronidazole, amoxicillin Cured This work
a

n, no. of cases reported.

b

Six specimens with anaerobic bacteria only and nine with mixed aerobic, facultative, and anaerobic bacteria over a series of 74 patients with postthoracotomy sternal wound infection.

c

Formerly Peptostreptococcus magnus.

d

Only local debridement was performed in this patient.