TABLE 1.
Yr (na) | Age/gender | Type of surgery | Prophylaxis | Bacteriological findings |
Antimicrobial therapy | Outcome | Reference | |
---|---|---|---|---|---|---|---|---|
Mediastinal fluid | Blood cultures | |||||||
1976 (1) | 65/Male | Coronary bypass | Cephalotin | Bacteroides fragilis | Bacteroides fragilis | Clindamycin | Cured | 7 |
1985 (2) | 65/Male | Coronary bypass | Cephapirin | Bacteroides brevis, Staphylococcus epidermidis | Bacteroides brevis | Clindamycin, ticarcillin, gentamicin | Cured | 15 |
44/Male | Coronary bypass | Cephapirin | Bacteroides fragilis, Staphylococcus epidermidis | Bacteroides fragilis | Clindamycin, nafcillin, gentamicin | Cured | ||
1988 (1) | 48/Male | Coronary bypass | Cefamandole | Bacteroides oralis, Staphylococcus epidermidis, α-hemolytic streptococci | Bacteroides fragilis | Clindamycin, vancomycin | Cured | 8 |
1989 (15b) | Various | Various | Various | 10 Peptostreptococcus isolates (including 4 Finegoldia magnac isolates/), and 4 Bacteroides, 2 Propionibacterium, and 2 Clostridium isolates | Not detailed | Various | Not detailed | 4 |
1996 (2) | 43/Female | Coronary bypass | Unknown | Staphylococcus aureus, Finegoldia magnac | Staphylococcus aureus | Vancomycin, gentamicin | Cured | 6 |
29/Male | Cardiac assist device | Unknown | Propionibacterium acnes, Staphylococcus epidermidis | Propionibacterium acnes | Vancomycin, penicillin | Cured | ||
2001 (4) | 7/Female | Ventricular septal defect | 1st-generation cephalosporin | Prevotella intermedia, Peptostreptococcus micros | Negative | Imipenem, amoxicillin-clavulanate | Cured | 5 |
3/Female | Ventricular septal defect | 1st-generation cephalosporin | Staphylococcus aureus, Bacteroides thetaiotaomicron, Peptostreptococcus prevotii | Staphylococcus aureus | Clindamycin, vancomycin | Cured | ||
5/Female | Fallot's tetralogy | 1st-generation cephalosporin | Escherichia coli, Clostridium perfringens | Escherichia coli | Clindamycin, vancomycin | Cured | ||
2/Male | Transposition of the great vessel | Penicillin | Prevotella melaninogenica, Peptostreptococcus species, Propionibacterium acnes | Prevotella melaninogenica | Ticarcillin-clavulanate, amoxicillin-clavulanate | Curedd | ||
2008 (1) | 50/Male | Coronary bypass | Cefamandole | Finegoldia magnac | Negative | Metronidazole, amoxicillin | Cured | This work |
n, no. of cases reported.
Six specimens with anaerobic bacteria only and nine with mixed aerobic, facultative, and anaerobic bacteria over a series of 74 patients with postthoracotomy sternal wound infection.
Formerly Peptostreptococcus magnus.
Only local debridement was performed in this patient.