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In vitro replication in bone marrow derived dendritic cells. Primary BMDCs were infected with WT HSV-1 at an MOI of 1 or 0.01. At indicated times postinfection, cells and supernatants were harvested and virus titers assayed on Vero cells. The results shown are the mean titers of three independent experiments. *, P < 0.05; **, P < 0.01.
