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. 2009 Sep 23;83(23):12368–12377. doi: 10.1128/JVI.01403-09

FIG. 3.

FIG. 3.

Growth characteristics of EBNA3C-HT LCLs transfected with EBNA3C point mutants. (A) Diagram of EBNA3C point mutants, indicating the RBP-Jκ binding mutant, SUMO binding mutant, and CtBP binding mutant. (B) Growth curves of EBNA3C-HT LCLs transfected with 15 μg of the oriP plasmid expressing control GFP, wt EBNA3C (E3C), or the indicated EBNA3C point mutant. These data are representative of results from four experiments (Table 1). (C) Western blotting for EBNA3C from complemented EBNA3C-HT LCLs on day 0 (2 days after transfection) and day 40. (D) Percentage of EBNA3C-HT LCLs in each stage of cell cycle after complementation with the indicated construct cultured in the absence of 4HT for 14 days.