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. Author manuscript; available in PMC: 2010 Dec 2.
Published in final edited form as: J Am Chem Soc. 2009 Dec 2;131(47):17328–17334. doi: 10.1021/ja907125t

Figure 4.

Figure 4

(a) Degranulation of IgE-sensitized RBL-2H3 mast cells stimulated by DNP-AuNPs (19.8-nm) of different ligand densities. For inhibition studies, cells were pre-incubated with DNP-AuNPs of 2.7 nM for 1 h at 37 °C and then stimulated by 0.1 μg/mL DNP-BSA for one additional hour. (b) Inhibition of degranulation stimulated by 0.1 μg/mL DNP-BSA, with DNP-AuNPs of (□) 10 and (●) 0 DNP on one nanoparticle.