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. 2009 Nov 2;119(12):3752–3764. doi: 10.1172/JCI38521

Figure 7. Nr0b2 mediates DES-induced alterations of histone H3K9 marks on the promoter of G9a target genes.

Figure 7

Shown are results of ChIP of crosslinked DNA from testes of P10 Nr0b2+/+ and Nr0b2L–/L– mice using H3K9me1 or H3K9me2 antibodies. The loci studied as G9a targets (290, 291, 110, Wfdc15a, and 282) were previously defined and cover at least 1 gene (35). The 282 locus was used as a negative control of H3K9 methylation. IgG was used as a negative internal control. For each condition, 6 ChIPs were performed. *P < 0.05 versus vehicle.