Figure 2. Future Challenges for Research in Pulmonary Hypertension.

There are a number of exciting avenues for research. These follow along the continuum of diagnosis, treatment and outcome. Early diagnosis may lead to earlier interventions of treatment. Ultimately, with individuals at particularly high risk for disease development, chemoprevention strategies could be employed. Treatment will focus on new, targeted pathways based on novel pathway investigations. The hope of combinatorial treatments are emerging. The field is in dire need of biomarker development to follow, more accurately, disease progression.