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. 2009 Oct 7;83(24):12790–12800. doi: 10.1128/JVI.01368-09

FIG. 3.

FIG. 3.

Alignment of the amino acid sequences of 11 HERV-K(HML-2) envelope proteins. The sequences of HERV-K101 (AF164609), K102 (AF164610), K104 (AC116309), K107 (AF164613), K108 (AC072054), K109 (AC055116), K115 (AY037929), Y178333, AP000776, and AC025420 are compared to the K113 (AY037928) wtEnv sequence. The consensus sequence and the putative original sequence (oricoEnv) obtained by applying an algorithm to identify shared polymorphisms (see Results for details) are included. The consensus and oricoEnv sequences differ at positions 137, 369, and 676 due to shared polymorphisms (highlighted by rectangles). The eight sites in HERV-K113 wtEnv changed to the consensus sequence in order to reconstitute the ancestral protein sequence are highlighted in gray.