. 2009 Oct 7;83(24):12738–12750. doi: 10.1128/JVI.01441-09

TABLE 1.

CD8⁺ T-cell phenotypes and functionality following single-vector administration^a

Cell expression	Results from administration of animals with:
	AAV8			SAdV24			AAVrh32.33
	% CD8	% IFN-γ	MFI	% CD8	% IFN-γ	MFI	% CD8	% IFN-γ	MFI
Tet⁺/CD8⁺	18.66 ± 5.66			5.74 ± 1.43			19.13 ± 2.37
IFN-γ⁺/CD8⁺	5.87 ± 1.22		12.81	6.51 ± 0.53		22.12	17.53 ± 2.18		18.26
IFN-γ⁺ CD107a⁻ TNF-α⁻ IL-2⁻/CD8⁺	0.21	3.58	6.66	0.06	0.92	8.45	0.80	4.56	8.51
IFN-γ⁺ CD107a⁺ TNF-α⁻ IL-2⁻/CD8⁺	3.49	59.45	8.80	2.33	35.79	12.83	8.28	47.23	11.27
IFN-γ⁺ CD107a⁺ TNF-α⁺ IL-2⁻/CD8⁺	1.95	33.22	15.90	2.97	45.62	28.87	8.56	48.83	25.2
IFN-γ⁺ CD107a⁺ TNF-α⁺ IL-2⁺/CD8⁺	0.01	0.17	NA	0.26	3.99	48.5	0.17	0.97	38.00

Splenocytes from AAV8-, SAdV24-, or AAVrh32.33-immunized mice (3 × 10¹⁰ GC; n = 4) were isolated 3 weeks postimmunization and subsequently analyzed with ICS and Gag tetramer and CD8 staining for the various cytokines and CD107a. NA, not applicable.