Table 1.

Confounding Variables in Glucose Measurement^a

Variable	Methodology affectedb
	GO	GD
Whole blood	↓	↓
Arterial	↑	↑
Capillary	↑	↑
Postprandial state	↑	↑
Hematocrit
Anemia	↑	↑
Polycythemia	↓	↓
Oxygen concentration
Hypoxia	↑	–
Oxygen therapy	↓	–
pH (6.8–7.55)
Low pH	– / ↓	–
High pH	– / ↑	–
Hypothermia	↑	↓ / ↑
Hypotension	↑	↓ / ↑
Drugs
Ascorbic acid	↓	↓ / -
Acetaminophen	↓	↑
Dopamine	–	↓
Icodextrin	–	↑
Mannitol	↑	–

^aCopyright © 2007 American Diabetes Association. From Diabetes Care®, Vol. 30, 2007: 403-409. Reprinted with permission from The American Diabetes Association.³⁸

^bChanges relative to venous plasma measured as central laboratory. GO, glucose oxidase; GD, glucose dehydrogenase.