Table 1.
Mean and Standard Deviation of Glycemia, Protocol Use and Mortality in Trials of Intensive Insulin Therapy.
| Glycemic control | Insulin protocol application | Mortality | |||||
|---|---|---|---|---|---|---|---|
| Conventional | IIT | Conventional | IIT | Conventional | IIT | p-value | |
| Leuven I trial5 | 8.5 ± 1.8 | 5.7 ± 1.1 | 307/783 (39.2%) | 755/765 (98.7%) | 63/783 (8.0%) | 35/765 (4.6%) | <0.04 |
| Leuven II trial17 | 8.5 ± 1.7 | 6.2 ± 1.6 | 426/605 (70%) | 580/595 (98%) | 162/605 (26.8%) | 144/595 (24.2%) | 0.31 |
| VISEP trial21 | 8.4 ± 1.8 | 6.2 ± 1.0 | 215/290 (74.1%) | 243/247 (98.4%) | 75/289 (26.0%) | 61/247 (24.7%) | 0.74 |
| NICE-SUGAR trial23 | 8.0 ± 1.3 | 6.4 ± 1.7 | 2080/3014 (69.0%) | 2931/3014 (97.2%) | 751/3012 (24.9%) | 829/3010 (27.5%) | 0.02 |