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. Author manuscript; available in PMC: 2009 Dec 2.
Published in final edited form as: J Allergy Clin Immunol. 2008 Nov 20;123(1):231–238.e4. doi: 10.1016/j.jaci.2008.10.011

FIG 4.

FIG 4

SEB promotes allergic responses to peanut at a low dose but not at a high dose. Responses to oral administration of 100 mg of WPE (WPElow) or 1 mg of WPE (WPEhigh) 6 10 mg of SEB were determined. Symptom scoring in response to challenge with 5 mg of WPE (A), peripheral blood eosinophilia (B), and WPE-specific IgE levels (C) was determined. Finally, in vitro cytokines on stimulation of splenocytes with 1 mg of WPE or anti-mouse CD3 (1 mg/mL) for 48 hours were studied. IL-4 (D), IL-5 (E), and IFN-g (F) levels are shown. *P < .05 and **P < .01. Student t test (n 5 5 per group).