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. 2009 Nov 16;106(48):20504–20509. doi: 10.1073/pnas.0908083106

Fig. 4.

Fig. 4.

Resistance of LTP induction at basal dendrites to the inhibitory effect of TNFα and Aβ1–42. High frequency stimulation (arrows) induced robust LTP of synaptic transmission at basal dendrites of CA1 pyramidal cells in the stratum oriens of animals injected i.c.v. with either vehicle (5 μL, n = 6, P < 0.05) (closed circles), TNFα (1.5 pmol, n = 6, P < 0.05) (open circles) or Aß1–42 (320 pmol, n = 6, P < 0.05) (triangles). Values are the mean percentage of pre-HFS baseline EPSP amplitude (±SEM). Calibration bars for EPSP traces: vertical, 0.5 mV; horizontal, 10 ms.