No enhancement of extinction of spatial memory in GCV-treated Nestin-tk transgenic mice. A, The experimental scheme. B, C, No difference in the latency (B) and distance swum (C) to reach the hidden platform between the tg-GCV and wt-GCV mice during acquisition (latency: ANOVA, F(1,20) = 0.138, p > 0.71; distance: ANOVA, F(1,20) = 0.238, p > 0.63; for tg-GCV, n = 12, for wt-GCV, n = 10). D, No difference in the duration in the target quadrants across the four probe trials between tg-GCV and wt-GCV mice (ANOVA, F(1,20) = 0.0035, p > 0.95). Error bars represent ± SEM.