Table 1. The predicted transmembrane (TM), intracellular loop (IL) and extracellular loop (EL) regions of the human CCR4 protein.
N terminus | mnptdiadttldesiysnyylyesipkpctkegi |
TM1 | kafgelflpplyslvfvfgllgnsvvvlvlfky |
IL1 | Klrs |
TM2 | mtdvyllnlaisdllfvfslpfwgyyaadq |
EL2 | Wfg |
TM3 | lglckmiswmylvgfysgiffvmlmsidrylaiv |
IL2 | havfslrart |
TM4 | ltygvitslatwsvavfaslpgfl |
EL2 | fstcyternhtycktkyslnsttw |
TM5 | kvlssleinilglviplgimlfcysmiirt |
IL3 | lqhcknekknk |
TM6 | avkmifavvvlflgfwtpynivlfletlve |
IL3 | levlqdctferyldyaiq |
TM7 | atetlafvhcclnpiiyfflgekfr |
C terminus | kyilqlfktcrglfvlcqycgllqiysadtpsssytqstmdhdlhdal |