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Drugs approved by the Food and Drugs Administration for treatment of fibromyalgia
| Drug | Class | Mechanism |
|---|---|---|
| Duloxetine | Antidepressant | Balanced norepinephrine and serotonin reuptake inhibition |
| Milnacipran | Antidepressant | Balanced norepinephrine and serotonin reuptake inhibition |
| Pregabalin | Anticonvulsant | α2δ ligand; affects calcium influx and release of excitatory amino acids and neuropeptides |
