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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Dermatol Clin. 2010 Jan;28(1):159–164. doi: 10.1016/j.det.2009.10.022

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Continual blistering and healing associated with severe generalized RDEB results in loss of normal anatomical oral features such as the palatal rugae leaving a smooth and ulcerated roof of the mouth.