Figure 2.
Increased recruitment of inflammatory cells to the airways of mice infected with small plaque variants of Beij/89. Mice were infected with 105 PFU of L, S or Mo viruses and, at day 3 or day 7 post-infection, mice were killed and BAL performed. BAL cells were centrifuged onto glass slides, stained with Diff Quick and the number of macrophages, neutrophils and lymphocytes were determined by nuclear morphology. Cell numbers from BAL of naïve (N) mice are included for comparison. Data represent the mean (± 1 SD) number of (A) macrophages, (B) neutrophils or (C) lymphocytes from groups of 5 mice and are representative of 2 independent experiments. * = p < 0.01, Kruskal-Wallis test.