Table 3.
Educational Performance and Alzheimer's Disease, All-Cause Dementia and Cognitive Impairment in the ADAMS Study (Odds Ratios and 95% Confidence Intervals).
Models | Predictors | Group | Possible/Probable Alzheimer's Disease (229 PPAD/307 normal) |
All Cause Dementia (300 Dementia/ 307 normal) |
Cognitive Impairment (Ordinal outcome with 118 CI/229 AD/307 normal) |
---|---|---|---|---|---|
Odds Ratio (95% CI) | Odds Ratio (95% CI) | Odds Ratio (95% CI) | |||
Model 1 | Educational Performance |
Below average (n=46) |
4.0 (1.2-14) | 4.3 (1.4-13) | 2.6 (1.3-4.9) |
Above average (n=189) |
0.9 (0.5-1.7) | 0.9 (0.5-1.6) | 1.0 (0.7-1.6) | ||
Average (n=424) |
1.0 | 1.0 | 1.0 |
Models adjusted for age, age-squared, sex, race, apolipoprotein E – ε4 presence, respondent's level of education, childhood SES (parents' highest level of education in years, family poverty (yes/no), family hardship (yes/no) or whether the father was absent) ; current SES (respondents' income and total current assets); comorbidities (self-reported medical history of high blood pressure, diabetes mellitus, heart disease, and stroke); and literacy as assessed by the Wide Range Achievement Test (W-RAT) Score