Table 3. Conserved modules and cis eSNPs can help elucidate common candidate genes from GWAS results.
FHS | Broad | Overlap | P | |
All lipid associating genes | 1,142 | 438 | 147 | 2.55×10−17 |
Genes with cis-eSNPs | 429 | 175 | 58 | 1.71×10−27 |
Genes in the conserved co-expression modules | 297 | 108 | 37 | 1.83×10−24 |
FHS: Framingham heart study; Broad: Broad Institute lipid study; P: FET p-value for the overlap.