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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Int J Biochem Cell Biol. 2009 Sep 22;42(1):17–20. doi: 10.1016/j.biocel.2009.09.009

Figure-1.

Figure-1

Polyol pathway of glucose metabolism. In polyol pathway aldose reductase (AR) catalyzes the reduction of glucose to sorbitol. Sorbitol is converted to fructose by sorbitol dehydrogenase. Both the steps require NADPH and NAD+ as co-factors.