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Rate constants for pseudo-first order reaction of DMPC clearance assay.
| ApoA-I Mutant | k (min−1) | Standard Error |
|---|---|---|
| WT | 1.00 | 0.00 |
| E198K | 0.767 | 0.23 |
| L42,44D | 1.59* | 0.07 |
| L46,47D | 1.77* | 0.09 |
Rate constants calculated by fitting first 5 min of clearancetime courses to pseudo -first order equation. All k values normalized to WT. The k-values shown are an average of two trials of independently prepared protein sets.
p<0.02 compared to WT by unpaired -2-tailed student’s t-test
