| Variably associated features |
| Autonomic dysfunction(30-33) |
| Large-fiber sensory neuropathy(26-28) |
| Psychiatric features: depression, anxiety, irritability(17, 25) |
| Cognitive decline and dementia(21) |
| Oculomotor dysfunction(80) |
| Focal dystonia (limb, cervical, laryngeal)(81, 82) |
| Spastic paraparesis(44) |
| Uncommon presentations |
| Essential tremor-like syndrome(9, 71) |
| MSA-like syndrome(32) |
| Rapidly progressive dementia(83) |
| CMT-like neuropathy(26) |
| Spastic paraparesis(44) |
|
Clinical heterogeneity within the same family(9, 84) |
