Table 3.

Relationship between BDNF and test score outcomes overall and stratified by case status.

Outcome	Population		Coefficient (SE)	P-Value
	Overall	Unadjusted	−0.003 (0.044)	0.95
		Adjusted1	0.053 (0.041)	0.20
CDR SUM	Cases	Unadjusted	0.009 (0.048)	0.85
		Adjusted2	0.016 (0.048)	0.74
	Controls	Unadjusted3	0.005 (0.003)	0.05
	Overall	Unadjusted	0.002 (0.020)	0.91
		Adjusted1	−0.019 (0.021)	0.36
CDR Global4	Cases	Unadjusted	−0.011 (0.026)	0.66
		Adjusted1	−0.029 (0.027)	0.28
	Overall	Unadjusted	0.017 (0.058)	0.77
		Adjusted1	−0.049 (0.055)	0.38
MMSE	Cases	Unadjusted	0.018 (0.065)	0.78
		Adjusted2	0.025 (0.069)	0.72
	Controls	Unadjusted3	−0.010 (0.017)	0.57

Covariates include in final adjusted models =

¹age only

²age and sex

³no covariates reached statistic significance

⁴no models included for controls because CDR Global Score = 0 for all subjects.