Table 1.

Densitometry assessment of % PDE6 phosphorylation in wild-type (WT) and transgenic retinal extacts. The irradiance (W/cm²), or the light source, was determined with a light meter containing a sensor fitted with a photopic filter. T22A, T35A and T22A-T35A mice received 1.67×10^-1 W/cm². Quantitative measurements of the bands were done with an AlphaImager with Software for Windows (AlphaInnotech, San Leandro, CA). D, dark-adapted; L, light-adaptedl; NS, non-significant.

	T35P (ng)	T22P (ng)	Total PDE6γ (ng)	%T35P/Total PDE6γ	%T22P/Total PDE6γ
Illumination at 1.67×10-1 W/cm2
WT L	19.65	11.30	82.21	33.67%	13.75%
WT D	30.27	7.14	80.30	37.69%	8.89%
T22A L	47.27	NS	78.13	60.50%
T22A D	36.50	NS	96.25	37.92%
T35A L	NS	NS	46.01
T35A D	NS	NS	54.30
T22A-T35A L	NS	NS	47.16
T22A-T35A D	NS	NS	36.43