Table 4. Univariate Analysis of Factors Associated with Change of Adherence Rate between 3 and 6 months for Intervention and Control Groups (N=66).
| Factors | N | Adherence rate change from 3 months Mean (SE) | P-value§ |
|---|---|---|---|
| Age (yrs) | 0.46 | ||
| <50 | 7 | 0.15 (0.08) | |
| 50 -59 | 12 | 0.08 (0.06) | |
| 60-69 | 21 | 0.19 (0.05) | |
| 70-79 | 18 | 0.11 (0.05) | |
| >=80 | 8 | 0.05 (0.08) | |
| Sex | 0.61 | ||
| Female | 30 | 0.14 (0.04) | |
| Male | 36 | 0.12 (0.04) | |
| Race | 0.32 | ||
| Black | 40 | 0.10 (0.03) | |
| White | 25 | 0.18 (0.04) | |
| Asian | 1 | 0.18 (0.22) | |
| Education | 0.67 | ||
| < High School | 9 | 0.09 (0.07) | |
| High School | 16 | 0.16 (0.06) | |
| College | 24 | 0.11 (0.05) | |
| Graduate School | 15 | 0.18 (0.06) | |
| General Health | 0.99 | ||
| Excellent | 12 | 0.13 (0.06) | |
| Good | 42 | 0.13 (0.03) | |
| Fair/poor | 12 | 0.13 (0.06) | |
| Depression score | 0.10 | ||
| <=0.1 | 22 | 0.13 (0.05) | |
| (0.1, 0.3] | 16 | 0.02 (0.05) | |
| (0.3, 0.7] | 14 | 0.18 (0.06) | |
| (0.7, 2.5] | 14 | 0.20 (0.06) | |
| Family income based on zip code | 0.11 | ||
| <=35 K | 20 | 0.07 (0.05) | |
| (35, 50]K | 13 | 0.16 (0.06) | |
| (50, 75]K | 16 | 0.07 (0.05) | |
| >75K | 16 | 0.23 (0.05) | |
| Glaucoma family history | 0.68 | ||
| None | 34 | 0.13 (0.04) | |
| 1 | 25 | 0.15 (0.04) | |
| ≥ 2 | 7 | 0.06 (0.08) | |
| Cup Disk ratio of worse eye | 0.42 | ||
| <=0.7 | 20 | 0.06 (0.05) | |
| (0.7, 0.8] | 20 | 0.18 (0.05) | |
| (0.8, 0.9] | 18 | 0.13 (0.05) | |
| >0.9 | 7 | 0.14 (0.08) | |
| Mean Deviation of worse eye | 0.25 | ||
| <=5 db | 28 | 0.12 (0.04) | |
| (5, 15] db | 13 | 0.22 (0.06) | |
| >15 db | 23 | 0.09 (0.05) | |
| IOP of worse eye | 0.32 | ||
| <=15 mmHg | 21 | 0.17 (0.05) | |
| (15, 17] mmHg | 12 | 0.18 (0.06) | |
| (17, 20] mmHg | 12 | 0.04 (0.06) | |
| >20 mmHg | 21 | 0.11 (0.05) | |
| Length of time on glaucoma medication | 0.08 | ||
| <= 1 year | 11 | 0.02 (0.07) | |
| > 1 year | 55 | 0.15 (0.03) | |
| Use of medicine | 0.04 | ||
| Unilateral | 18 | 0.04 (0.05) | |
| Bilateral | 48 | 0.16 (0.03) | |
| Use of other glaucoma medications | 0.20 | ||
| Only on travoprost | 29 | 0.08 (0.04) | |
| On a second agent | 26 | 0.18 (0.04) | |
| On three or more agents | 11 | 0.13 (0.07) | |
| Institute | 0.03 | ||
| JHU | 50 | 0.16 (0.03) | |
| PENN | 16 | 0.02 (0.05) | |
| Compliance rate at 3 months | 0.27 | ||
| <=0.50 | 28 | 0.16 (0.04) | |
| 0.501-0.75 | 38 | 0.10 (0.04) | |
| Treatment Group | 0.01 | ||
| Control | 31 | 0.06 (0.04) | |
| Intervention | 35 | 0.19 (0.04) |
SE= standard error; SD = standard deviation; yrs = years; K=thousand dollars. db=decibels; IOP= intraocular pressure; mmHg= millimeters of mercury; JHU = Wilmer Eye Institute; PENN = Scheie Eye Institute
§
From one-way analysis of variance.
†
Adjusted by treatment group assignment.