Table 5. Multivariate Analysis for Factors Associated with Change of Adherence Rate between 3 and 6 Months for Randomized Intervention and Control Groups (N=62*).
| Factors | N | Adherence rate change from 3 months Adjusted Mean (SE) | P-value§ |
|---|---|---|---|
| Treatment Group | 0.0001 | ||
| Control | 28 | -0.002 (0.04) | |
| Intervention | 34 | 0.21 (0.05) | |
| Adherence rate at Month 3 | 0.003 | ||
| <=0.50 | 26 | 0.18 (0.04) | |
| 0.501-0.75 | 36 | 0.03 (0.05) | |
| Race | 0.02 | ||
| Black | 37 | 0.04 (0.04) | |
| White | 25 | 0.17 (0.05) | |
| Education | 0.051 | ||
| < High School | 8 | 0.09 (0.07) | |
| High School | 16 | 0.18 (0.05) | |
| College | 24 | 0.01 (0.05) | |
| Graduate School | 14 | 0.14 (0.06) | |
| I have used travoprost without using the device during the study | 0.12 | ||
| Never | 43 | 0.14 (0.04) | |
| Ever | 19 | 0.06 (0.05) | |
| Use of medicine | 0.16 | ||
| Unilateral | 17 | 0.04 (0.05) | |
| Bilateral | 45 | 0.16 (0.03) | |
| Age (yrs) | 0.65 | ||
| <50 | 7 | 0.11 (0.08) | |
| 50 -59 | 11 | 0.07 (0.06) | |
| 60-69 | 21 | 0.16 (0.05) | |
| 70-79 | 16 | 0.13 (0.05) | |
| >=80 | 7 | 0.05 (0.07) | |
| Length of time on glaucoma medication | 0.67 | ||
| <= 1 year | 9 | 0.09 (0.07) | |
| > 1 year | 53 | 0.12 (0.03) |
*
3 patients were excluded from the multivariate analysis due to missing value in education status (n=2) and use of travoprost without using the device during the study (n=1), Asian was also excluded due to small number (n=1).
SE = standard error; yrs = years
§
From one-way analysis of variance
Note: All the independent variables included in the multivariate model are listed above.