FIG. 10.

TNF- α–inducible genes that were specifically downregulated after DC treatment but not by C₉₅ curcumin: the focal adhesion pathway. The genes shown in cluster Fig. 8B were subjected to functional analysis by using DAVID (NIAID, NIH). One of the major known pathways (KEGG) identified in this category was the focal adhesion pathway, as shown. The gene candidates that were differentially expressed in response to DC are marked with asterisks. DAVID, Database for Annotation, Visualization, and Integrated Discovery; KEGG, Kyoto Encyclopedia of Genes and Genomes. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article at www.liebertonline.com/ars).