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. 2009 Mar;11(3):449–468. doi: 10.1089/ars.2008.2230

FIG. 14.

FIG. 14.

Demthylcurcumin (DC) downregulated TNF- α–induced ICAM-1 and VCAM-1 protein expression in HMEC cells. Human microvascular endothelial cells (HMECs) were seeded in six-well plates (0.5 × 106/well). DC or C95 was added to the cells for 24 h and then activated with TNF-α for 24 h. A significant decrease in (A) ICAM-1 and (B) VCAM-1 protein expression was noted with DC treatment but not the C95 treatment. Results are expressed as mean ± SD, p < 0.05; *, compared with TNF-α treated.