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Demethylcurcumin, but not C50 or C95 curcumin, protected HT4 neuronal cells against glutamate-induced death. HT4 cells were seeded in six-well plates (0.1 × 106/well). Demethylcurcumin (DC), C50, or C95 was added to the cells for 8 h before glutamate (10 mM) exposure. Results are expressed as mean ± SD, p < 0.05; *compared with glutamate-treated.
