Table 1.
Perceived Benefits and Barriers by Likelihood to Refer to Clinical Trials and Medical Specialty
| Likelihood to refer to clinical trial | Medical Specialty | |||||
|---|---|---|---|---|---|---|
| BENEFITS (%) | Not likely (n=162) |
Likely (n=193) |
p-value | PCP (n=229) |
Specialist (n=141) |
p-value |
| Patient and/or Family may benefit from participation | 67.4 | 88.3 | <.001 | 75.5 | 69.5 | ns |
| Patient and/or Family is interested in research participation | 73.6 | 84.0 | .02 | 78.6 | 68.1 | .03 |
| Participation by the patient may enhance ongoing medical care | 62.2 | 82.1 | <.001 | 70.3 | 65.2 | ns |
| I may receive helpful feedback to guide my care decisions | 43.0 | 66.0 | <.001 | 55.9 | 42.6 | .01 |
| BARRIERS (%) | ||||||
| The risks of participation appear to be too great | 63.2 | 72.8 | ns | 67.7 | 58.9 | ns |
| Patient may be unable to give informed consent | 51.8 | 51.2 | ns | 53.7 | 41.8 | .03 |
| Patient may be exposed to uncomfortable procedures or risks | 45.6 | 50.6 | ns | 50.7 | 37.6 | .02 |
| Family may find participation too overly burdensome | 62.2 | 66.7 | ns | 61.6 | 60.3 | ns |
| Not practical based on distance of my patient from the research site | 55.4 | 59.3 | ns | 66.7 | 44.7 | .004 |
| Patient has expressed no interest in research | 46.1 | 43.2 | ns | 44.1 | 40.4 | ns |
| Lack of awareness of research studies | 45.1 | 43.2 | ns | 41.9 | 42.6 | ns |
| Lack of time to discuss research participation during clinical visits | 43.0 | 35.8 | ns | 42.8 | 29.1 | .008 |
PCP = Primary Care Provider
Ns = not significant